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Controversies in Stroke Care: Incl/Excl tPA

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Controversies in Stroke Care: Incl/Excl tPAProgram Date: Jan. 20, 2012

Estimated Time: 1 hour

This activity is jointly sponsored by Medical Education Resources and National Stroke Association.

Accreditation for this program has expired. This program is for informational purposes.

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Program Overview

Controversies in Stroke Care: Redefining Exclusion/Inclusion Criteria for IV tPA Use will address use of IV tPA in the following situations:

  • Mild or rapidly improving symptoms
  • Anticoagulants
  • Seizures

Goals and Learning Objectives

Through participation in this activity, participants should be better able to:

  • Discuss the history and background of NINDS’ tPA study criteria
  • Evaluate their respective hospital’s protocol for using IV tPA in acute ischemic stroke
  • Describe a rationale for modifying current IV tPA treatment protocols

Target Audience

The target audience for this activity includes neurologists, neuroscience nurses, emergency department physicians and nurses, and hospitalists.

Content Developed and Presented By

Mark J. Alberts, MD
Professor of Neurology
Chief of the Division of Stroke and Cerebrovascular Disease Northwestern University
Feinberg School of Medicine 
Director of the Stroke Program Northwestern Memorial Hospital
Chicago, Illinois

James C. Grotta, MD
Director, Vascular Neurology Program
Professor and Chairman, Department of Neurology
Roy M. and Phyllis Gough Huffington Distinguished Chair UTHealth Medical School
Houston, Texas

Arthur Pancioli, MD
Professor and Chairman of the Department of Emergency Medicine University of Cincinnati
Cincinnati, Ohio

Disclosure of Conflict of Interest

Medical Education Resources ensures balance, independence, objectivity and scientific rigor in all its educational activities. In accordance with this policy, Medical Education Resources identifies conflicts of interest with its instructors, content managers and other individuals who are in a position to control the content of an activity. Medical Education Resources resolves conflicts to ensure that all scientific research referred to, reported or used in a CME activity conforms to the generally accepted standards of experimental design, data collection and analysis. Medical Education Resources is committed to providing its learners with high-quality CME activities that promote improvements or quality in healthcare and not the business interest of a commercial interest.

Faculty Disclosures

The faculty reported the following financial relationships with commercial interests whose products or services may be mentioned in this CME activity:

Name of Faculty Reported Financial Relationship
Mark J. Alberts, MD Consultant and speaker for Genentech, Inc.
James C. Grotta, MD   Grant/research support for Lundbeck
Arthur Pancioli, MD Consultant for Banyan International (Advisor Committee)

The content managers reported the following financial relationships with commercial interests whose products or services may be mentioned in this activity:

Name of Content Managers Reported Financial Relationship
Denise Henasey, National Stroke Association No financial relationships to disclose
Victoria C. Smith, MD, MER No financial relationships to disclose
Veronda Smith, FNP-BC, MER No financial relationships to disclose


The content and views presented in this educational activity are those of the authors and do not necessarily reflect those of Medical Education Resources, National Stroke Association, and/or Genentech, Inc. and Penumbra, Inc.. The authors have disclosed if there is any discussion of published and/or investigational uses of agents that are not indicated by the FDA in their presentations. The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Medical Education Resources, National Stroke Association and/or Genentech, Inc.  and Penumbra, Inc..  MER’s ANCC accreditation status does not imply endorsement by MER or ANCC of any commercial products displayed in conjunction with this activity. Before prescribing any medicine, primary references and full prescribing information should be consulted. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. The information presented in this activity is not meant to serve as a guideline for patient management.

System requirements:

PC-based attendees—Required: Windows® 2000, XP Home, XP Pro, 2003 Server, Vista or newer.
Macintosh®-based attendees—Required: Mac OS X 10.4 (Tiger®) or newer.

To view MER’s Privacy Policy:

For questions regarding this activity, please contact us at or Medical Education Resources at

The Controversies in Stroke Care webinar series is brought to you by an educational grant from Genentech, Inc. and Penumbra, Inc.

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