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Epidemiology of Atrial Fibrillation and Stroke

Clinical Studies of New Oral Anticoagulants

Practice Guidelines

Prevention

Additional Online Resources for Clinicians


Note: Some resources listed below may require a log-in or paid membership to access.

 

 

Epidemiology of Atrial Fibrillation and Stroke

Publications

 

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Clinical epidemiology of atrial fibrillation and related cerebrovascular events in the United States. Neurologist. 2008;14:143-150.

 

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Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study. Neurology. 1978;28:973-978.

Online resources

 

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Framingham Heart Study


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

Clinical Studies of New Oral Anticoagulants

Apixaban publications

 

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Apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial: design and rationale. Am Heart J. 2010;159:331-339.

 

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Apixaban in patients with atrial fibrillation. NEJM. 2011;364:806-817.

 

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Apixaban versus warfarin in patients with atrial fibrillation. NEJM. 2011;365:981-992.

 

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Apixaban with antiplatelet therapy after acute coronary syndrome. NEJM. 2011;365:699-708.

 

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Dual antiplatelet therapy or apixaban in patients ineligible for vitamin-K antagonists for stroke prevention in atrial fibrillation: lessons from the recent aspirin-controlled trials. J Am Coll Cardiol.  2011;57:E61.

 

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Effect of apixaban an oral direct and selective factor Xa inhibitor on inflammatory biomarkers following acute coronary syndrome. J Am Coll Cardiol. 2011;57:E1039.

Dabigatran publications

 

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Anticoagulant options—why the FDA approved a higher but not a lower dose of dabigatran. NEJM. 2011;364:1788-1790.

 

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Cost analysis of substituting dabigatran for warfarin in an anticoagulation management service. J Am Coll Cardiol. 2011;57:E1188.

 

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Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation. Ann Intern Med. 2011;154:1-11.

 

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Cost-effectiveness of dabigatran for stroke prophylaxis in atrial fibrillation. Circulation. 2011;123:2562-2570.

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Dabigatran challenges warfarin’s superiority for stroke prevention in atrial fibrillation. Stroke. 2010;41:1307-1309.

 

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Dabigatran etexilate versus warfarin in patients with different types of atrial fibrillation: a RE-LY® subgroup analysis. J Am Coll Cardiol. 2011;57:E62.

 

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Dabigatran versus warfarin and impact of CHAD2-VASC score on outcome in atrial fibrillation patients: a RE-LY subgroup analysis. J Am Coll Cardiol. 2011;57:E7.

 

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Dabigatran versus warfarin in atrial fibrillation patients with low, moderate and high CHADS2 score: a RE-LY subgroup analysis. J Am Coll Cardiol. 2010;55:A1,E2. 

 

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Dabigatran versus warfarin in patients with atrial fibrillation. NEJM. 2009;361:1139-1151.

 

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Dabigatran versus warfarin in the treatment of acute venous thromboembolism. NEJM. 2009;361:2342-2352.

 

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Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial. Circulation. 2011;123:2363-2372.

Rivaroxaban publications

 

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Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. NEJM. 2011;365:883-891.

Editorials and reviews

 

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Can we rely on RE-LY? NEJM. 2009;361:1200-1202.

 

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A new era for anticoagulation in atrial fibrillation. NEJM. 2011. doi:10.1056/NEJMe1109748.

 

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The new oral anticoagulants. Blood. 2010;115:15-20.

 

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Therapeutic potential of oral factor Xa inhibitors. NEJM. 2010;363:2559-2561.

Online resources

 

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Stroke Trials Registry—A database of ongoing and completed clinical trials

 


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

Practice Guidelines

Publications

 

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2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011;57:223-242.

 

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2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011;57:1330-1337.

 

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AHA/ASA Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:227-276.

 

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Guidelines for the management of atrial fibrillation, the task force for the management of atrial fibrillation of the European Society of Cardiology (ESC). Euro Heart J. 2010;31:2369-2429. doi:10.1093/eurheartj/ehq278.

 

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Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:517-584.

 

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Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor based approach: The Euro Heart Survey on Atrial Fibrillation. Chest. 2010;137:263-272. doi:10.1378/chest.09-1584.

 

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Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ. 2011;342:d124.

  

Online resources

 

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ACCF/AHA pocket guideline: management of patients with atrial fibrillation

 

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Top eight differences among the AF guidelines: Canadian, European, and US

 


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

Prevention

Publications

 

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Identifying patients at high risk for stroke despite anticoagulation: a comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke. 2010;41:2731-2738.

 

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Performance of stroke risk scores in older people with atrial fibrillation not taking warfarin: comparative cohort study from BAFTA trial. BMJ. 2011;342:d3653.

 

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Potentially preventable strokes in high-risk patients with atrial fibrillation who are not adequately anticoagulated. Stroke. 2009;40:235-240.

 

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Stroke risk and antithrombotic strategies in atrial fibrillation. Stroke. 2010;41:2705-2713.

Online resources

 

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CHADS2 Calculator for Atrial Fibrillation Stroke Risk

 

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CHA2DS2-VASc Calculator for Atrial Fibrillation Stroke Risk

 

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Heart Rhythm Society Webinar on Stroke Prevention in Patients with Atrial Fibrillation

 


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

Additional Online Resources for Clinicians

Continuing medical education

 

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ASHP Advantage—Atrial Fibrillation Webinars, CME and Podcasts

 

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Atrial Fibrillation in Primary Care (AFIP)—A Tool for Primary Care Physicians

 

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Cleveland Clinic Center for Continuing Education—Atrial Fibrillation

 

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Heart Rhythm Society—Atrial Fibrillation Awareness: Education for Healthcare Professionals

 

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Heart Rhythm Society—Atrial Fibrillation Webcasts

 

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PRESAGEcme™ Peer-to-Peer Podcast Series

Other related websites

 

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American College of Physicians Foundation—Initiative on Atrial Fibrillation and Stroke Prevention

 

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Atrial Fibrillation—A CardioSource Clinical Community

 

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The Heart.org

 

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The Internet Stroke Center

 


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

Access online videos

 

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National Stroke Association: Beat Your OddsSM Educational Toolkit and Patient Video

 

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Heart Rhythm Society Public Service Announcement: A-Fib Feels Like

 


Epidemiology | Clinical Studies | Practice Guidelines | Prevention | Resources for Clinicians 

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